Publication details

Diagnostické možnosti zobrazovacích metod v hodnocení morfologického korelátu kognitivních změn u pacientů s roztroušenou sklerózou

Title in English Imaging techniques to evaluate morphological correlates of cognitive dysfunction in multiple sclerosis patients
Authors

OBHLÍDALOVÁ Ivana KEŘKOVSKÝ Miloš ŠTOURAČ Pavel BEDNAŘÍK Petr VLČKOVÁ Eva

Year of publication 2012
Type Article in Periodical
Magazine / Source Česká a slovenská neurologie a neurochirurgie
MU Faculty or unit

Faculty of Medicine

Citation
Field Neurology, neurosurgery, neurosciences
Keywords multiple sclerosis; cognitive dysfunction; magnetic resonance; magnetization transfer; functional magnetic resonance; diffusion tensor imaging; spectroscopy; positron emission tomography
Description Cognitive dysfunction in patients with multiple sclerosis is quite common and has a great impact on the quality of patient's social and professional life. High frequency and severity of these symptoms encourage objectivization of their morphological correlates. Besides the conventional magnetic resonance imaging techniques, commonly used for the disease diagnostics and activity monitoring, alternative procedures, such as magnetization transfer imaging, functional magnetic resonance, MR spectroscopy or diffusion tensor imaging, are also available. The use of the majority of these techniques is currently rather experimental and their practical application is under intensive investigation.

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