Publication details
Erythema migrans
| Authors | |
|---|---|
| Year of publication | 2012 |
| Type | Article in Periodical |
| Magazine / Source | Klin Mikrobiol Inf Lék. |
| MU Faculty or unit | |
| Citation | |
| Field | Epidemiology, infectious diseases and clinical immunology |
| Keywords | Lyme borreliosis; early localized stage; erythema migrans; Borrelia burgdorferi sensu lato |
| Description | The article summarizes the latest knowledge about etiology, epidemiology, pathogenesis, clinical signs, diagnostic procedures and therapy of cutaneous borrelial infection – erythema migrans (EM). The sole focus on this clinical entity is intentional since EM is the most common clinical involvement of Lyme borreliosis (LB) in the Czech Republic (CR). New genospecies from complex Borrelia burgdorferi sensu lato: B. lusitaniae and B. spielmanii as etiologic agents are reported, although there are no commercial tests available yet for their detection, but the ticks are demonstrably infected with them in Europe and probably even in CR. Six pathogenic genospecies circulate between vertebrates and Ixodes ricinus ticks in Europe. Transmission cycle in nature, hosts identified as reservoirs and distribution of borreliae in Europe are presented. Clinical forms of EM are described in detail including accompanying features. Types of erythema in USA and Europe are compared. In the part on differential diagnosis, allergies, dermatologic and infectious diseases with similar appearance on the skin as EM are mentioned. Though the diagnosis of EM is exclusively clinical and serology is not indicated, methods of direct detection and two-tier testing of antibodies are discussed. Therapeutic recommendation argues the choice of antibiotics from those available in CR. |