Publication details

The pig as a experimental model for clinical craniofacial research

Authors

ŠTEMBÍREK Jan KYLLAR Michal PUTNOVÁ Iveta STEHLÍK M. BUCHTOVÁ Marcela

Year of publication 2012
Type Article in Periodical
Magazine / Source Laboratory Animals
MU Faculty or unit

Faculty of Medicine

Citation
Doi http://dx.doi.org/10.1258/la.2012.012062
Field ORL, ophthalmology, stomatology
Keywords Pig; experimental animal model; oral cavity; teeth; maxilla; mandible
Description The pig represents a useful, large experimental model for biomedical research. Recently, it has been used in different areas of biomedical research. The aim of this study was to review the basic anatomical structures of the head region in the pig in relation to their use in current research. Attention was focused on the areas that are frequently affected by pathological processes in humans: the oral cavity with teeth, salivary gland, orbit, nasal cavity and paranasal sinuses, maxilla, mandible and temporomandibular joint. Not all of the structures have an equal morphology in the pig and human, and these morphological dissimilarities must be taken into account before choosing the pig as an experimental model for regenerative medicine.

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