Publication details

Neuroborreliosis versus sclerosis multiplex

Authors

MIKOLÁŠEK Peter KRBKOVÁ Lenka HOMOLA Lukáš ČAPOVOVÁ Iva HABANEC Tomáš RUSNÁKOVÁ Štefánia DAŇKOVÁ Marie VARADYOVÁ Barbora SKOTÁKOVÁ Jarmila

Year of publication 2013
Type Article in Periodical
Magazine / Source Pediatrie pro praxi
MU Faculty or unit

Faculty of Medicine

Citation
Field Paediatry
Keywords neuroborreliosis; multiple sclerosis; cerebrospinal fluid
Description Clinical symptoms in neuroborreliosis and multiple sclerosis can be similar at the begining of the disease. Basic laboratory values in both diseases are quite non-specific, may be normal, or imitate a variety of other clinical entities. Therapeutic algorithm, severity of course and particulary the possibility of permanent disability due to late diagnosis and treatment delay are quite different. Although there are molecular mimicry hypotheses of lyme borreliosis as a potential trigger for multiple sclerosis (MS), there is not enough definitive evidence for this opinion. The subject of this article is differential diagnosis, proper initiation and duration of therapy, including a case report of a patient who fulfilled the clinical and laboratory criteria for both the MS and for neuroborreliosis. Key words: neuroborreliosis, multiple sclerosis, cerebrospinal fluid.

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