Publication details
Štítná žláza, diabetes a gravidita
| Title in English | Thyroid gland, diabetes and pregnancy |
|---|---|
| Authors | |
| Year of publication | 2013 |
| Type | Article in Periodical |
| Magazine / Source | Postgraduální medicína |
| MU Faculty or unit | |
| Citation | |
| Field | Endocrinology, diabetology, metabolism, nutrition |
| Keywords | thyroid gland during pregnancy; disorders of menstrual cycle and fertility in cases of thyropathies; postnatal thyroidal dysfunctions |
| Description | Disorders of the menstruation cycle and problems with fertility are a common clinical symptom of thyroid gland function disorders. Hypothyroidism tends to cause longer menstrual cycle, oligomenorrhoea or even sterility. The prevalence among pregnant women is around 3-4%, it can adversely influence the course of the pregnancy and it is associated with a risk of malformations of the foetus. During pregnancy, it is necessary to quickly saturate the patient with thyroid hormones and to keep their levels close to the upper limits of the normal range. Hyperthyroidism is characterised by frequent, irregular anovulatory cycles and infertility, which means that pregnancy is rare in such cases (0.1-0.2%) and due to immunologic tolerance, the consumption of thyrostatics usually quickly decreases. If there occurs and persists a serious thyrotoxicosis during pregnancy it means a risk of damage to the foetus and neonatal It is necessary to administer thyrostatics in full doses and to indicate thyreidectomy in the 2nd trimester. Gestation thyrotoxicosis (prevalence of around 2.4% of pregnancies) is a form of non-autoimmune hyperthyroidism associated with heightened secretion of HCG around the 10th week of the pregnancy, the clinical image of thyrotoxicosis occurs in around 50% of those cases. |