Publication details
THE OUTCOME IN CHILDREN WITH CONGENITAL CYTOMEGALOVIRUS INFECTION
| Authors | |
|---|---|
| Year of publication | 2013 |
| Type | Conference abstract |
| MU Faculty or unit | |
| Citation | |
| Description | Objectives: In this report, the authors have presented clinical picture, course and therapy used in 23 infants with congenital CMV, hospitalised at the Department of Child Infectious Diseases in Faculy Hospital Brno within January 1998 - December 2012. Methods: The diagnosis of congenital.infection was established on the base of typical symptoms of congenially acquired disease, in a part of infants even from personal anamnesis (mother's disease during pregnancy) and verified by PCR CMV DMA and by serological examinations. Result: In the set of 23 newborns with confirmed congenital CMV infection, 14 of them have permanent neurological sequel. 5 of them suffer from sensoric affection (4 x disturbance up to loss of hearing, 1x eye lesion). Conclusions: As most maternal infections are asymptomatic, repeated serological screening of all suscetible seronegative woman would be required through! pregnancy. There is no established treatment for congenital CMV infection, although ganciclovir have been suggested for use to inhibit disease progression. |