Publication details
HYPERTENZE V TĚHOTENSTVÍ
| Title in English | HYPERTENSION IN PREGNANCY |
|---|---|
| Authors | |
| Year of publication | 2013 |
| Type | Article in Periodical |
| Magazine / Source | Kardiológia pre prax |
| MU Faculty or unit | |
| Citation | |
| Field | Cardiovascular diseases incl. cardiosurgery |
| Keywords | hypertension; pregnancy; gestational hypertension; preeclampsia; treatment of hypertension |
| Description | Hypertension complicates 5-10% pregnancies and is responsible for substantial maternal, foetal and neonatal morbidity and mortality. The definition of hypertension in pregnancy is not unanimous, the oné based on absolute blood pressure (BP) values (systolic BP > 140 oř diastolic BP >90mmHg) is now preferred. Hypertension in pregnancy is not a single entity and is divided to 4 groups: pre-existing hypertension, gestational hypertension, preexisting hypertension and superimposed gestational hypertension with proteinuria and unclassifiable hypertension. Non-pharmacological treatment of hypertension should be considered in women with BP of 140-150/90-99 mm Hg. Salt restriction or weight reduction is not recommended. Drug treatment in all pregnant women with BP 150/95 is recommended. Antihypertensive treatment should be considered at values BP s 140/90 mm Hg in women with gestational hypertension, preexisting hypertension with the superimposition of gestational hypertension or hypertension with target organ damagc. Methyldopa, labetalol, calcium-channel blockers and beta-blockers are drugs of choice. ACE inhibitors and ATI blockers are contraindicated in pregnancy. For severe and complicated hyperten-sion labetalol i.v. and oral nifedipine might be administered. Drugs of second choice in hypertensive emergencies are nitroprus-side i.v. oř urapidil. All antihypertensive drugs taken by the nursing mother are excreted into breast milk, but most of them are present at very low concentrations. Hypertension in pregnancy is a marker for future cardiovascular and metabolic diseases. |