Publication details
Reprodukční ochrana u dospívajících dívek s maligním onemocněním
| Title in English | Fertility preservation in adolescent women with newly diagnosed cancer |
|---|---|
| Authors | |
| Year of publication | 2014 |
| Type | Article in Periodical |
| Magazine / Source | Onkologie |
| MU Faculty or unit | |
| Citation | |
| Field | Gynaecology and obstetrics |
| Keywords | infertility; reproductive protection; GnRH anlogues; ovarian tissue cryopreservation; oocyte vitrification |
| Description | Effective treatment of cancer often causes patients irreversible damage of reproductive abilities. Modern markers ovarian reserves are introduced. These clinical examinations can effectively help to evaluate the risk of irreversible damage of gonadal cells done by oncology disease or its curative treatment. The paper describes current oncofertility techiques implemented to clinical practice - embryo and oocyte banking, ovarian tissue cryopreservation including further possibility of its orthotopic autotransplantation and administration of gonadoliberin analogues for ovarian protection. Attention is applied to pro and contras of previously described methods of ovarian protection in the discussion. Brief practical outcomes and recommendations are given for consultation caretakers in adolescent female cancer patients threatened with significant fertility loss. |