Publication details

The need to improve current psychopharmacotherapy before developing new drugs

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Authors

ČEŠKOVÁ Eva

Year of publication 2014
Type Article in Periodical
Magazine / Source EXPERT OPINION ON PHARMACOTHERAPY
MU Faculty or unit

Central European Institute of Technology

Citation
Web http://informahealthcare.com/doi/abs/10.1517/14656566.2014.941806
Doi http://dx.doi.org/10.1517/14656566.2014.941806
Field Neurology, neurosurgery, neurosciences
Keywords genotyping; non- adherence; phenotyping; psychopharmacotherapy; therapeutic drug monitoring; treatment optimization
Description CNS research has become unprofitable, and several pharmaceutical companies have reduced financial support for developing new CNS drugs. Until the situation can be changed, it is our duty to optimize the usage of the currently available psychoactive drugs. Several tools for optimizing pharmacotherapy are available, such as therapeutic drug monitoring and genotyping and phenotyping CYP enzymes. Further medical treatment and healthcare provision for patients with severe mental disorders should be improved. Knowledge of psychopharmacotherapy influences the choices of medication and outcomes; therefore, future psychiatrists should have a greater knowledge of pharmacodynamics, pharmacokinetics and pharmacogenetics.
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