Publication details

Dentálne abnormality po protinádorovej liečbe v detskom veku

Title in English Dental Abnormalities after Tratment for childhood cancer
Authors

MLADOSIEVIČOVÁ Beata JURKOVIČ Richard IZAKOVIČOVÁ HOLLÁ Lydie

Year of publication 2015
Type Article in Periodical
Magazine / Source Klinická onkologie
MU Faculty or unit

Faculty of Medicine

Citation
Doi http://dx.doi.org/10.14735/amko201520
Field ORL, ophthalmology, stomatology
Keywords chemotherapy; radiotherapy; late effects; tooth abnormalities; childhood cancer
Description Childhood cancer therapy often increases the risk of dental complications, such as tooth and roots agenesis, microdontia, abnormal development of tooth enamel, increased risk of cavity and other abnormalities. In a comparison with other late adverse effects of chemotherapy, radiotherapy and hematopoietic stem cell transplantion, a relative small number of clinical studies observing patients for more than two years after completion of anticancer treatment was published. In this article, we review the incidence of dental abnormalities caused by commonly used anticancer treatment modalities as well as discuss their risk factors. Early identification of high-risk patients, early detection and management of dental abnormalities and better education of patients or their guardians, may have an impact on quality of life of cancer survivors.

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