Publication details
Léčba anémie a nedostatku železa u chronického srdečního selhání
| Title in English | Treatment of anaemia and iron deficiency in chronic heart failure |
|---|---|
| Authors | |
| Year of publication | 2014 |
| Type | Article in Periodical |
| Magazine / Source | Kardiologická revue - Interní medicína |
| MU Faculty or unit | |
| Citation | |
| Field | Cardiovascular diseases incl. cardiosurgery |
| Keywords | anaemia; iron deficiency; heart failure; therapy of anaemia |
| Description | Iron deficiency is an important co-morbidity in patients with heart failure. A major factor in the pathogenesis of anaemia, it is also a separate condition with serious clinical consequences (e. g. impaired exercise capacity) and poor prognosis in heart failure patients. Experimental evidence suggests that iron therapy in iron-deficient patients may activate molecular pathways that can be cardio-protective. Clinical studies have demonstrated favourable effects of IV iron on the functional status, quality of life, and exercise capacity in HF patients. IV iron supplementation has become a novel therapy in HF patients with iron deficiency. |