Publication details
MALDI-TOF fingerprinting of the whole mammalian cell-lines
| Authors | |
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| Year of publication | 2014 |
| Type | Appeared in Conference without Proceedings |
| MU Faculty or unit | |
| Citation | |
| Description | Robust cell-lines identification requires reliable databases of cell-lines fingerprints. Mass spectrometric fingerprinting of mammalian cell-lines is a promising way to achieve the goal of fast, cheap, simple and reliable cell-lines authentication. However, general and standardized method for mass spectrometric fingerprinting of the whole mammalian cell-lines is not available to date. We developed, optimized and validated MALDI-TOF mass spectrometric method for reliable, specific and reproducible whole-cell fingerprinting of mammalian cell-lines. Quality and robustness of mass spectrometric fingerprints is demonstrated by statistical analysis of experimental data. Developed method for the whole mammalian cell-lines fingerprinting, in contrast to actual procedures, is inexpensive, fast and it opens the door towards routine cell authentication. |
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