Publication details
Mají natriuretické peptidy novou šanci v léčbě srdečního selhání?
| Title in English | Do the natriuretic peptides have a new chance in the treatment of heart failure? |
|---|---|
| Authors | |
| Year of publication | 2014 |
| Type | Article in Periodical |
| Magazine / Source | Vnitřní lékařství |
| MU Faculty or unit | |
| Citation | |
| Field | Cardiovascular diseases incl. cardiosurgery |
| Keywords | inhibitors of vasopeptidases; natriuretic peptides; heart failure |
| Description | The influence of natriuretic peptides on cardiovascular and renal system is a source of potentional possibilities of treatment of hypertension and heart failure. Synthetic natriuretic peptide neseritide showed a short time haemodynamic benefit, however the long time benefit and influence on renal functions was questionable.New hope in the treatment of chronic heart failure and hypertensive patients might be ularitid and new substance LCZ696 which is a dual inhibitor of neprilysin and angiotensin receptor. Clinical trials with these substances are ongoing. |