Publication details

Lignany ze schisandry čínské - látky perspektivní pro medicínu

Title in English Lignans from Chinese Schisandra – Promising Medicinal Substances
Authors

VYMAZAL Ondřej SLANINOVÁ Iva

Year of publication 2015
Type Article in Periodical
Magazine / Source Živa
MU Faculty or unit

Faculty of Medicine

Citation
Field Biochemistry
Keywords Schisandra chinensis; multidrug resistance; dibenzocyclooctadiene lignans; ABC transporter; P-glycoprotein; natural products
Description Schisandra chinensis has been used in traditional Chinese medicine for its antimicro­bial, antiviral, antimycotic and antioxida­tive effects. The main active compounds are dibenzocyclooctadiene lignans, which inhibit membrane ABC-transporters, re­sponsible for the multi-drug resistance of cancer cells during their treatment by cyto­statics.

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