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Publication details
Multimodální farmakologické působení trazodonu
Title in English | Multimodal pharmacological actions of trazodone |
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Authors | |
Year of publication | 2015 |
Type | Article in Periodical |
Magazine / Source | Psychiatrie |
MU Faculty or unit | |
Citation | |
Web | http://www.tigis.cz/images/stories/psychiatrie/2015/01/09_sulcova_psych_1-15.pdf |
Field | Psychiatry, sexuology |
Keywords | trazodone ; multimodal mechanisms ; efficacy ; dosage forms |
Description | Trazodone was primarily classified as tetracyclic antidepressant, later known as a member of the subgroup SARI (Serotonin2 Antagonists/Reuptake Inhibitors), according to the main confirmed pharmacological mechanisms of action, which correspond beside antidepressant also to anxiolytic and hypnotic effects. A successive investigation of multimodal trazodone affinities and activities at neuronal binding sites is extending the view on its therapeutic potential. This article summarizes that currently available information. |
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