Publication details
Srdeční transplantace
| Title in English | Heart transplantation |
|---|---|
| Authors | |
| Year of publication | 2014 |
| MU Faculty or unit | |
| Citation | |
| Description | Heart transplantation (HTX) has become an accepted treatment for selected patients with end-stage heart failure. There are two transplant centres in Czech republic – Prague, since 1984 and Brno since 1992.The chapter contains indication for heart transplantation, the use of left ventricle assisst devices, operation itself and long term complications and follow-up. Pharmacotherapy after heart transplantation includes the problems of immunosuppression and interactions of immunosuppressant drugs and their adverse effects. Posttransplant complications include infections, metabolic disorders ( hypertension, hyperlipidemia, diabetes mellitus), ulcer disease, hematological disorders, nephropathy, hepatopathy, neuropathy, osteoporosis and development of malignancies, especially cutaneous and lymphomas. Nevertheless the survival after heart transplantation is very good: one year 85%, five years 78% and 10 years 58%. |