Publication details
Dokáže rybí olej zlepšit hojení ran v chirurgii?
| Title in English | Can fish oil improve wound healing in surgery? |
|---|---|
| Authors | |
| Year of publication | 2016 |
| Type | Article in Periodical |
| Magazine / Source | Vnitřní lékařství |
| MU Faculty or unit | |
| Citation | |
| Field | Surgery incl. transplantology |
| Keywords | anti-inflammatory agent; cicatrix; fish oil; macrophage; omega-3 fatty acid; resolution of inflammation; Toll-like receptor; wound healing |
| Description | A surgical insult induces both local and systemic inflammatory responses which, if inappropriate, could impair wound healing. According to many studies omega-3 polyunsaturated fatty acids from fish oil improve the process of wound healing by their immunomodulatory effect. In contrast to current anti-inflammatory drugs, which could alter immune defence and impair the resolution of inflammation, omega-3 fatty acids have a simultaneous anti-inflammatory pro-resolution effect which is not immunosuppressive. Besides that they improve cicatrix quality. With regard to this effect they prevent excessive or prolonged inflammation and wound complications. |