Publication details
Noncompaction of the left ventricle. A case report
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| Year of publication | 2016 |
| Type | Conference abstract |
| Citation | |
| Description | The noncompaction of the left ventricle is a congenital dysfunction of ventricular morphogenesis, occurs because of arrested development of muscle fiber compaction, a process that normally takes place in early embryogenesis. The arrested morphological and functional development of the heart muscle is characterized by hypertrabeculation and deep recesses in the ventricular wall. Although this rare disorder is defined as a congenital genetic cardiomyopathy and usually is diagnosed in pediatric population, it has become more frequently identified in adult patients. The mortality and morbidity were high due to congestive heart failure, arrhythmias and systemic thromboembolism. This case presents that 8 year-old-boy had an operated congenital cardiovascular disease and transposition of great artery disease found as dead in the house. At autopsy, in internal examination, new ostium on the basis of ascending aorta, graft material on the upper part of interventricular septum and wide trabeculations in the right and left ventricular in heart, hyperemia on the surface and in the sections of the lungs were found. In histopathologic examination, in the sections of heart, differentiation of trabeculations in the myocard, polypoid hypertrabeculations from subendocardial layer to epicardial fat tissue, endocardial fibrosis, sinusoidal cavities due to anastomosing of trabecules, enlargement of cytoplasm in muscle fibers and interstitiel fibrosis, in the sections of lungs, edema in alveolus, extravasation of erythrocytes and macrophages and in the bronchioles, chronic inflammation cells were detected. In chemical examination, 101 ng/ml chlorpheniramine in blood and in urine ibuprofen and chlorpheniramine were found. It was reported that death occurred due to pneumonia. Although death occurred due to pneumonia, we aimed to present this rare pathological finding with autopsy and histopathologic findings, laboratory results in medicolegal literature. |