Publication details
Vliv fyzické zátěže na vybrané imunitní a fyziologické parametry
| Title in English | The Influence of physical exertion on selected immunological and physiological parameters |
|---|---|
| Authors | |
| Year of publication | 2016 |
| Type | Article in Periodical |
| Magazine / Source | Československá fyziologie |
| MU Faculty or unit | |
| Citation | |
| Field | Immunology |
| Keywords | C3 part of complement; chronic fatigue syndrome; immune parameters; immunoglubulin IgG; IgM and IgA; ultramarathon |
| Description | Chronic fatigue syndrome is a disease detected in recent 15 or 20 years. Overtrained athletes, people living in stress, the ones with disturbed immunity or people suffering from some of the infectious diseases are the most threatened ones. During ultra-long-distance run, human immune, physiological a biochemical parameters drift of their physiological ranges. The values could increase or decrease. The samples of serum of ultramarathon runners, who took part in the National Ultramarathon Mastership, were collected and measured before and after the race. The parameters include IgA, IgM, IgG and C3 part of complement. Statistically important increases in IgA and IgG concentrations after the race were observed. The changes of concentrations of IgM and C3 part of complement was not statistically important. IgG is responsible for the activation of complement, secondary immune reactions and the neutralization of bacterial toxins. IgA in the role of muckal imunoglobulin helps immune cells to swallow heterogenous particles, germs and toxins. Our immune systém is more threatened by heterogenous infectious diseases and even the chronic fatigue syndrome. |