Publication details
Polyfarmakoterapie nahlížená nejen prismatem multimorbidity, ale jako další geriatrický syndrom
| Title in English | Polypharmacy viewed not only through the prism of multi-morbidity, but also as a independent geriatric syndrome |
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| Authors | |
| Year of publication | 2016 |
| Type | Article in Periodical |
| Magazine / Source | Vnitřní lékařství |
| MU Faculty or unit | |
| Citation | |
| Field | Other specializations of internal medicine |
| Keywords | Old age; geriatrisation of medicine; multi-morbidity; polypharmacy; prescription; randomized clinical trials; evidence based medicine |
| Description | Polypharmacy is common in the elderly, especially in the late age (over 75 years). Usually it is closely related to the geriatric multi-morbidity. The authors highlight the medication used in the anticipated positive and potential negative potential. While physicians often must make difficult trade-offs between the guidelines on one hand and complicated multiple morbidity, on the other hand, while trying to avoid polypharmacy (5 or more drugs), especially excessive polypharmacy (10 or more drugs). Multimorbid elderly patients who are treated in accordance with guidelines typically use large amounts of medicaments. This polypharmacy increases the risk of adverse drug reactions and drug interactions. The authors point out the pitfalls of performance of large clinical studies and EBM on one side and the daily clinical practice at the risk of their indiscriminate application, albeit with good intentions to improve the health of seniors. |