Publication details

Studie SPRINT - co přinesla nejvýznamnější studie posledního období v oblasti hypertenze

Title in English The SPRINT study - the outcomes of the most important study over the recent period focused on hypertension
Authors

SOUČEK Miroslav

Year of publication 2016
Type Article in Periodical
Magazine / Source Vnitřní lékařství
MU Faculty or unit

Faculty of Medicine

Citation
Field Other medical specializations
Keywords target values; hypotension; cardiovascular events; systolic blood pressure
Description When treating systolic hypertension we do not know the optimum blood pressure which leads to the reduction of cardiovascular events and cardiovascular and total mortality. The results of the ACCORD study, when comparing intensive treatment of systolic blood pressure < 120mm Hg and standard treatment < 140mm Hg, did not lead to affecting the primary target for patients with diabetes mellitus. In the autumn last year the SPRINT study was presented and published, showing favourable impact on the combined primary target, which involved myocardial infarction, other acute coronary syndromes, stroke, heart failure or death from cardiovascular causes during intensive treatment of systolic blood pressure, i.e. < 120 mm Hg, but on the other hand with a statistically significant incidence of secondary effects (hypotension, syncope, renal impairment or failure).

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