Efficiency of acidemia correction on intermittent versus continuous hemodialysis in acute methanol poisoning

• Authors: ZAKHAROV Sergey; PELCLOVA Daniela; NAVRATIL Tomas; BELACEK jaromie; LATTA Jiri; PISAR Michal; RULISEK Jan; LEPS Jiri; ZIDEK Pavel; KUCERA Cyril; BOCEK Robert; MAZUR Miroslav; BELIK Zdenek; CHALUPA Josef; TALAFA Viktor; KONDRAS Kamil; NALOS Daniel; SEDLAK Ctirad; ŠENKYŘÍK Michal; SMID Jan; SALEK Tomas; ROBERT Darren M.; HOVDA Knut Erik
• Year of publication: 2017
• Type: Article in Periodical
• Magazine / Source: Clinical Toxicology
• MU Faculty or unit: Faculty of Medicine
• Web: http://dx.doi.org/10.1080/15563650.2016.1250901
• Doi: http://dx.doi.org/10.1080/15563650.2016.1250901
• Field: Other medical specializations
• Keywords: Acidemia; continuous veno-venous hemodialysis; extended daily hemodialysis; intermittent hemodialysis; metabolic acidosis; methanol poisoning
• Description: Acidemia is a marker of prognosis in methanol poisoning, as well as compounding formate-induced cytotoxicity. Prompt correction of acidemia is a key treatment of methanol toxicity and methods to optimize this are poorly defined. Objective: We studied the efficiency of acidemia correction by intermittent hemodialysis (IHD) and continuous renal replacement therapy (CRRT) in a mass outbreak of methanol poisoning.