Publication details
Activity of ring-substituted 8-hydroxyquinoline-2-carboxanilides against intestinal sulfate-reducing bacteria Desulfovibrio piger
| Authors | |
|---|---|
| Year of publication | 2018 |
| Type | Article in Periodical |
| Magazine / Source | MEDICINAL CHEMISTRY RESEARCH |
| MU Faculty or unit | |
| Citation | |
| Web | https://link.springer.com/article/10.1007/s00044-017-2067-7?shared-article-renderer |
| Doi | http://dx.doi.org/10.1007/s00044-017-2067-7 |
| Field | Microbiology, virology |
| Keywords | 8-Hydroxyquinolines; Sulfate-reducing bacteria; Lipophilicity; Electronic parameter; Structure–activity relationships |
| Description | Desulfovibrio genus is dominant among sulfate-reducing bacteria (SRB) in the large intestine of healthy people and animals. It is mostly isolated from patients with inflammatory bowel disease (IBD) and can be involved in the disease initiation. Primary in vitro screening of 8-hydroxyquinoline-2-carboxanilides was performed against Desulfovibrio piger Vib-7 representing SRB. |