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Informace o publikaci
Activity of ring-substituted 8-hydroxyquinoline-2-carboxanilides against intestinal sulfate-reducing bacteria Desulfovibrio piger
Autoři | |
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Rok publikování | 2018 |
Druh | Článek v odborném periodiku |
Časopis / Zdroj | MEDICINAL CHEMISTRY RESEARCH |
Fakulta / Pracoviště MU | |
Citace | |
www | https://link.springer.com/article/10.1007/s00044-017-2067-7?shared-article-renderer |
Doi | http://dx.doi.org/10.1007/s00044-017-2067-7 |
Obor | Mikrobiologie, virologie |
Klíčová slova | 8-Hydroxyquinolines; Sulfate-reducing bacteria; Lipophilicity; Electronic parameter; Structure–activity relationships |
Popis | Desulfovibrio genus is dominant among sulfate-reducing bacteria (SRB) in the large intestine of healthy people and animals. It is mostly isolated from patients with inflammatory bowel disease (IBD) and can be involved in the disease initiation. Primary in vitro screening of 8-hydroxyquinoline-2-carboxanilides was performed against Desulfovibrio piger Vib-7 representing SRB. |