Publication details

Myastenie a anestezie

Title in English Myasthenia gravis and anesthesia
Authors

VOHÁŇKA Stanislav HORÁKOVÁ Magda

Year of publication 2017
Type Article in Periodical
Magazine / Source Neurologie pro praxi
MU Faculty or unit

Faculty of Medicine

Citation
Field Neurology, neurosurgery, neurosciences
Keywords neuromuscular junction; myasthenia gravis; neuromuscular blocking agents; cholinesterase inhibitors
Description Myasthenia gravis is an autoimmune disorder of neuromuscular transmission. There are many drugs frequently used in anesthe-siology which interfere significantly with this disease. The most important are peripheral blocking agents and potent inhaled anesthetic agents. Patients suffering from myasthenia reveal modified sensitivity to these drugs, esp. to the peripheral blocking agents. Regional methods of the anesthesia or combination of both are preferred. Postoperative management is based on the careful monitoration of patients until full recovery is reached. In patient with myasthenia gravis there is no risk of malignant hyperthermia.

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