Selectivity of original C-hexopyranosyl calix[4]arene conjugates towards lectins of different origin

• Authors: KAŠÁKOVÁ Martina; MALINOVSKÁ Lenka; KLEJCH Tomáš; HLAVÁČKOVÁ Martina; DVOŘÁKOVÁ Hana; FUJDIAROVÁ Eva; ROTTNEROVÁ Zdeňka; MAŤÁTKOVÁ Olga; LHOTÁK Pavel; WIMMEROVÁ Michaela; MORAVCOVÁ Jitka
• Year of publication: 2018
• Type: Article in Periodical
• Magazine / Source: Carbohydrate Research
• MU Faculty or unit: Central European Institute of Technology
• Web: http://dx.doi.org/10.1016/j.carres.2018.08.012
• Doi: http://dx.doi.org/10.1016/j.carres.2018.08.012
• Keywords: Glycomimetics; Lectin; C-glycosides; Polyvalency; calix[4]arene
• Description: Original C-alpha-(D-manno/D-galacto/L-fuco)pyranosyl calix [4]arene-based constructs were synthesized and their affinity towards 7 lectins was evaluated using in vitro and in vivo assays.

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