Nonhuman primates across sub-Saharan Africa are infected with the yaws bacterium Treponema pallidum subsp pertenue

• Authors: KNAUF Sascha; GOGARTEN Jan F.; SCHUENEMANN Verena J.; DE NYS Helene M.; DUX Ariane; STROUHAL Michal; PAŠTĚKOVÁ Lenka; BOS Kirsten I.; ARMSTRONG Roy; BATAMUZI Emmanuel K.; CHUMA Idrissa S.; DAVOUST Bernard; DIATTA Georges; FYUMAGWA Robert D.; KAZWALA Reuben R.; KEYYU Julius D.; LEJORA Inyasi A. V.; LEVASSEUR Anthony; LIU Hsi; MAYHEW Michael A.; MEDIANNIKOV Oleg; RAOULT Didier; WITTIG Roman M.; ROOS Christian; LEENDERTZ Fabian H.; ŠMAJS David; NIESELT Kay; KRAUSE Johannes; CALVIGNAC-SPENCER Sebastien
• Year of publication: 2018
• Type: Article in Periodical
• Magazine / Source: EMERGING MICROBES & INFECTIONS
• MU Faculty or unit: Faculty of Medicine
• Doi: http://dx.doi.org/10.1038/s41426-018-0156-4
• Keywords: Treponema pallidum
• Description: The bacterium Treponema pallidum (TP) causes human syphilis (subsp. pallidum; TPA), bejel (subsp. endemicum; TEN), and yaws (subsp. pertenue; TPE). Although syphilis has reached a worldwide distribution, bejel and yaws have remained endemic diseases. Bejel affects individuals in dry areas of Sahelian Africa and Saudi Arabia, whereas yaws affects those living in the humid tropics. Yaws is currently reported as endemic in 14 countries, and an additional 84 countries have a known history of yaws but lack recent epidemiological data. Although this disease was subject to global eradication efforts in the mid-20th century, it later reemerged in West Africa, Southern Asia, and the Pacific region5. New large-scale treatment options triggered the ongoing second eradication campaign, the goal of which is to eradicate yaws globally by 2020.