Publication details
Controlled photorelease of alkynoic acids and their decarboxylative deprotection for copper-catalyzed azide/alkyne cycloaddition
Authors | |
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Year of publication | 2018 |
Type | Article in Periodical |
Magazine / Source | Chemical communications |
MU Faculty or unit | |
Citation | |
Web | https://pubs.rsc.org/en/Content/ArticleLanding/2018/CC/C8CC03341B#!divAbstract |
Doi | http://dx.doi.org/10.1039/c8cc03341b |
Keywords | PHOTOREMOVABLE PROTECTING GROUPS; ONE-POT SYNTHESIS; COUPLING REACTIONS; BORON DIPYRROMETHENE; CARBOXYLIC-ACIDS; CLICK CHEMISTRY; PROPIOLIC ACID; ARYL IODIDES; GREEN LIGHT |
Description | A controlled photorelease of alkynoic acids from the meso-methyl BODIPY photoremovable protecting group facilitates their subsequent efficient decarboxylation to give terminal alkynes for a Cu-I-catalyzed azide/ alkyne cycloaddition. The quantum efficiencies of the photochemical step and the kinetics of the click reaction step are reported. |
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