Publication details
Subtype definition of vascular parkinsonism
| Authors | |
|---|---|
| Year of publication | 2018 |
| Type | Article in Periodical |
| Magazine / Source | PARKINSONISM & RELATED DISORDERS |
| MU Faculty or unit | |
| Citation | |
| Doi | http://dx.doi.org/10.1016/j.parkreldis.2018.03.005 |
| Keywords | OLDER-ADULTS; DISEASE; DENERVATION; SIGNS |
| Description | We thank Dr. Levin for expressing interest in our work. Dr. Levin applies a traditional clinico-anatomic perspective to interpret our proposed criteria, pointing out that our criteria do not exclusively require that vascular lesions be located within specific topographic regions, such as the nigrostriatal and striato-thalamo-cortical pathways. At the same time, Dr. Levin notes the often observed clinical scenario in which patients with extensive and confluent vascular lesions on brain MRI scans may be fully asymptomatic motor-wise despite the fact that some of these lesions may be located in regions of critical motor circuitry. This scenario shows that factors other than the geographic location of vascular lesions in the brain may play a role in the pathogenesis of vascular parkinsonism (VaP). |