Publication details
Parkinsonova nemoc
| Title in English | Parkinson's disease |
|---|---|
| Authors | |
| Year of publication | 2019 |
| MU Faculty or unit | |
| Citation | |
| Description | Parkinson's disease is one of the so-called neurodegenerative diseases whose symptoms are related to neuronal death in various areas of the nervous system - the brain, but also in other parts of the central and peripheral nervous systems. The most visible symptoms are caused by the death of nerve cells in deep areas of the brain - the so-called basal ganglia. According to available scientific data, neuronal death is induced by accumulation of protein (called alpha-synuclein). This protein is a common and necessary part of communication between nerve cells. In some diseases, including Parkinson's disease, it is over-accumulated in nerve cells (neurons) and thus affects their activity. The most affected neurons are involved in the production of an important chemical substance - dopamine, which in the brain is responsible for numerous functions (regulation of movement, mood and the like). The main part of currently available treatment for Parkinson's disease, which you can read in the next section of this brochure, is targeted to supplement the missing dopamine. |