Publication details
THE BIOCHEMICAL PROCESS OF LUBRICANT FILM FORMATION IN JOINT REPLACEMENT
| Authors | |
|---|---|
| Year of publication | 2018 |
| Type | Article in Proceedings |
| Conference | ENGINEERING MECHANICS 2018 PROCEEDINGS, VOL 24 |
| MU Faculty or unit | |
| Citation | |
| Web | https://www.engmech.cz/im/proceedings/show_p/2018/725 |
| Doi | http://dx.doi.org/10.21495/91-8-725 |
| Keywords | synovial fluid; film formation; Raman spectroscopy; bio-tribology; tribo-chemistry |
| Description | The main objective of this study is to clarify the biochemical reactions of the formation of the lubricating film between the head and the cup of the joint replacement. The chemical changes taking place within the proteins of synovial fluid constitute after joint replacements need to be observed. Film formation is also dependent on the pH of the solution and static and rolling conditions, viscosity, concentration of the solution and other mechanical properties of the total environmental condition of joint replacement. The chemical composition of synovial fluid is predominantly considered to explain the development of film on the ball. The experiment was conducted in ball-on-cup configuration in a hip joint simulator, where the ball was made of cobalt chromium molybdenum alloy and the cup was of optical glass. The used proteins albumin, gamma-globulin and bovine serum were the reactants of this process. To analyze the products of the reaction, Raman spectroscopic method was used to observe the changes among proteins. After the analysis of the Raman spectra, it is assumed heterogeneous catalysis process could be taken place on the metal ball during chemical reaction. The results could have significant information regarding lubricating film development within the joint replacement. |
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