Suitability of 3D culture system with GrowDex for longterm culture of granulosa cells

• Authors: CHMELÍKOVÁ E.; SEDMÍKOVÁ M.; JEŠETA Michal; POSTLEROVÁ P.; KREJČÍŘOVÁ R.; KREJČOVÁ T.; HAVLÍKOVÁ K.; ŽÁKOVÁ Jana; VENTRUBA Pavel
• Year of publication: 2020
• Type: Conference abstract
• MU Faculty or unit: Faculty of Medicine
• Description: Study question: Is it possible to increase the suitability of in vitro culture system for long-term granulosa cells cultivation using three dimensional (3D) culture with hydrocellulose GrowDex? Summary answer: Using of 3D long-term culture system with GrowDex resulted in increasing of anti-apoptotic Bcl-2 and decreasing of pro-apoptotic Bax factors in porcine granulosa cells