Publication details

Method of diagnosis of colorectal cancer

Authors

SLABÝ Ondřej VYCHYTILOVÁ Petra SVOBODA Marek ŠACHLOVÁ Milana

Year of publication 2020
Type Patent
MU Faculty or unit

Central European Institute of Technology

Publisher European Patent Office
State Germany
Patent's number EP3431609B1
Web odkaz na stránku Evropského patentového úřadu
Description The present invention relates to a method of diagnosing and prognosing colorectal cancer using piRNA-hsa-5937, having the sequence TCCCTGGTGGTCTAGTGGTTAGGATTCGGCA (SEQ ID NO. 1), as a biomarker. The biomarker can be combined with other piRNAs or miRNAs. The resulting method uses a body fluid as the input, and therefore is non-invasive, has a high sensitivity and specificity even in very early stages of the disease, and is cost-effective.
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