Publication details

Mukoaktivní látky v léčbě kašle

Title in English Mucoactive agents in treating cough
Authors

VRANOVÁ Vilma VAŠUT Karel

Year of publication 2020
Type Article in Periodical
Magazine / Source Pediatrie pro praxi
MU Faculty or unit

Faculty of Pharmacy

Citation
Web https://www.solen.cz/artkey/ped-202005-0008_mukoaktivni_latky_v_lecbe_kasle.php?back=%2Fsearch.php%3Fquery%3Dvranova%26sfrom%3D0%26spage%3D30
Doi http://dx.doi.org/10.36290/ped.2020.070
Keywords cough; mucoactive substances
Description Cough is a fundamental defence mechanism that maintains clear airways; moreover, phlegm production is an integral part of a non-specific protective immune response in the respiratory tract. The above facts have to be taken into account and respected when choosing an optimal cough pharmacotherapy. For mucosal healing, it is appropriate to promote mucociliary clearance, surfactant production, and other physiological functions. The action of mucoactive agents is not restricted to altering the rheological properties of mucus; these drugs also stimulate surfactant production, have antioxidant properties, reduce oxidative stress, decrease bacterial adherence, and affect the action of antibiotics.

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