Publication details

NBQX attenuates relapse of nicotine seeking but not nicotine and methamphetamine self-administration in rats

Authors

RUDÁ Jana AMCHOVÁ Petra ŠIŠKA Filip TIZABI Yousef

Year of publication 2021
Type Article in Periodical
Magazine / Source The World Journal of Biological Psychiatry
MU Faculty or unit

Faculty of Medicine

Citation
Web https://www.tandfonline.com/doi/full/10.1080/15622975.2021.1907714
Doi http://dx.doi.org/10.1080/15622975.2021.1907714
Keywords AMPA/kainate receptor; Nicotine; Methamphetamine; Self-administration; Relapse
Description Pharmacological manipulations of glutamatergic ionotropic receptors have been suggested as a promising target for addiction treatment. Antagonists of AMPA/kainate receptors were shown to reduce alcohol intake or alcohol-seeking in various animal models. In this study, we evaluated the effect of NBQX, an AMPA/kainate receptor antagonist, on methamphetamine (METH) and nicotine self-administration in rats.
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