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NBQX attenuates relapse of nicotine seeking but not nicotine and methamphetamine self-administration in rats
Název česky | NBQX snižuje relaps vyhledávání nikotinu, ale ne operantní příjem nikotinu či metamfetaminu u potkana |
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Autoři | |
Rok publikování | 2021 |
Druh | Článek v odborném periodiku |
Časopis / Zdroj | The World Journal of Biological Psychiatry |
Fakulta / Pracoviště MU | |
Citace | |
www | https://www.tandfonline.com/doi/full/10.1080/15622975.2021.1907714 |
Doi | http://dx.doi.org/10.1080/15622975.2021.1907714 |
Klíčová slova | AMPA/kainate receptor; Nicotine; Methamphetamine; Self-administration; Relapse |
Popis | Pharmacological manipulations of glutamatergic ionotropic receptors have been suggested as a promising target for addiction treatment. Antagonists of AMPA/kainate receptors were shown to reduce alcohol intake or alcohol-seeking in various animal models. In this study, we evaluated the effect of NBQX, an AMPA/kainate receptor antagonist, on methamphetamine (METH) and nicotine self-administration in rats. |
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