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Molekulární testování u karcinomu endometria / společné doporučení ČOS, onkogynekologické sekce ČGPS, SROBF a SČP ČLS JEP
Title in English | Molecular testing in endometrial carcinoma - joint recommendation of Czech Oncological Society, Oncogynecological Section of the Czech Gynecological and Obstetrical Society, Society of Radiation Oncology, Biology and Physics, and the Society of Czech Pat |
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Authors | |
Year of publication | 2021 |
Type | Article in Periodical |
Magazine / Source | ČESKÁ GYNEKOLOGIE-CZECH GYNAECOLOGY |
MU Faculty or unit | |
Citation | |
Web | https://www.cs-gynekologie.cz/casopisy/ceska-gynekologie/2021-4-6/molekularni-testovani-u-karcinomu-endometria-spolecne-doporuceni-cos-onkogynekologicke-sekce-cgps-srobf-a-scp-cls-jep-127962 |
Doi | http://dx.doi.org/10.48095/cccg2021264 |
Keywords | endometrial carcinoma; molecular testing; POLE (DNA polymerase epsilon); mismatch repair system; p53 |
Description | Molecular classification of endometrial carcinoma is becoming an important part of the diagnostic process with direct therapeutic implications. Recent international guidelines, including the joint recommendation of the European Society of Gynaecological Oncology, the European Society for Radiotherapy and Oncology and the European Society of Pathology include the molecular classification into standard diagnostic algorithms. Molecular testing of endometrial carcinomas is also recommended in the latest (5th edition) of the World Health Organization classification of female genital tumors. Due to the need to implement these recommendations in practice, representatives of four professional societies of the Czech Medical Association of J. E. Purkyne (the Czech Oncological Society, the Oncogynecological Section of the Czech Gynecological and Obstetrical Society, the Society of Radiation Oncology, Biology and Physics, and the Society of Czech Pathologists) organized a meeting focused on this topic. Recommendation for molecular testing of endometrial carcinoma in routine diagnostic practice in the Czech Republic. |