Publication details

Hepatitis E - epidemiology and clinical course in the largest cohort in the Czech Republic.

Authors

MIHALČIN Matúš HUSOVÁ Libuše VAŠÍČKOVÁ Petra BENA Marcel HUSA Petr

Year of publication 2022
Type Article in Periodical
Magazine / Source Archives of Medical Science
MU Faculty or unit

Faculty of Medicine

Citation
Web https://www.archivesofmedicalscience.com/Hepatitis-E-epidemiology-and-clinical-course-in-the-largest-cohort-in-the-Czech-Republic,152338,0,2.html
Doi http://dx.doi.org/10.5114/aoms/152338
Keywords therapy; epidemiology; Czech Republic; Eastern Europe; hepatitis E; hepatitis E virus; viral zoonosis
Description Introduction: The majority of hepatitis E (HE) reports come from Western Europe. The aim of the study was to describe the typical epidemiological and clinical characteristics of HE in the Czech Republic. Material and methods: The retrospective analysis of 173 patients with HE. Results: At least 90% of cases were autochthonous (HEV-3 genotype). Seventeen patients were treated with ribavirin. Five underwent liver transplants because of fulminant HE. We noted neurological symptomatology in 9 cases. Six patients developed chronic HE. Conclusions: There is a possibility of severe health complications caused by the hepatitis E virus in the Czech Republic.

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