Publication details

Use of Magnetic Resonance Imaging to Quantify Fat and Steatosis in the Pancreas in Patients after Bariatric Surgery: a Retrospective Study

Authors

BLAHO Martin MACHACKOVA Jitka DÍTĚ Petr HOLECZY Pavol SEDIVY Petr PSAR Robert SVAGERA Zdenek VILIMEK Dominik TOMAN Daniel URBAN Ondrej BUZGA Marek

Year of publication 2022
Type Article in Periodical
Magazine / Source OBESITY SURGERY
MU Faculty or unit

Faculty of Medicine

Citation
Web https://link.springer.com/article/10.1007/s11695-022-06278-4
Doi http://dx.doi.org/10.1007/s11695-022-06278-4
Keywords Obesity; Bariatric surgery; Metabolic syndrome; Pancreatic steatosis
Description invasive method for diagnosing PS. We investigated the impact of metabolic syndrome (MS) on the presence of PS, differences in individuals with and without PS, and the metabolic effects of bariatric procedures. Methods Changes in anthropometric and basic biochemistry values and MS occurrence were evaluated in 34 patients with obesity who underwent a bariatric procedure. After the procedure, patients underwent MRI with manual 3D segmentation mask creation to determine the pancreatic fat content (PFC). We compared the differences in the PFC and the presence of PS in individuals with and without MS and compared patients with and without PS. Results We found no significant difference in the PFC between the groups with and without MS or in the occurrence of PS. There were significant differences in patients with and without PS, especially in body mass index (BMI), fat mass, visceral adipose tissue ( VAT), select adipocytokines, and lipid spectrum with no difference in glycemia levels. Significant metabolic effects of bariatric procedures were observed. Conclusions Bariatric procedures can be considered effective in the treatment of obesity, MS, and some of its components. Measuring PFC using MRI did not show any difference in relation to MS, but patients who lost weight to BMI < 30 did not suffer from PS and had lower overall fat mass and VAT. Glycemia levels did not have an impact on the presence of PS.

You are running an old browser version. We recommend updating your browser to its latest version.

More info