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Publication details
Pyoderma gangrenosum u nespolupracující pacientky
Title in English | Uncooperative patient with pyoderma gangraenosum |
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Authors | |
Year of publication | 2022 |
Type | Article in Periodical |
Magazine / Source | Referátový výběr z dermatovenerologie |
MU Faculty or unit | |
Citation | |
Web | http://referatovyvyber.cz/dermatovenerologie/images/flippingbook/RVD-4-2022/rvd-4-2022.pdf |
Keywords | Pyoderma gangraenosum; neutrophil dysfunction; treatment |
Description | Pyoderma gangraenosum is a re_latively rare disease of unknown etiology, first described more than 100 years ago. It is necessary to think about it in sudden, painful and non-healing ulcers, most often on legs. A lot of patients have systemic di_seases (Crohn's disease, ulcerative colitis, arthritis, malignancies). The treatment is empirical. Treatment can be divided into four categories: topical treatment, systemic non-immunosuppressive therapy, syste_mic immunosuppressive therapy and biological therapy. Ulcers heal with cribriform scars. The course is difficult to predict, often recurrent, depending on the type and severity of comorbidities. |