Publication details

Pyoderma gangrenosum u nespolupracující pacientky

Title in English Uncooperative patient with pyoderma gangraenosum
Authors

NEVŘALOVÁ Klára JEDLIČKOVÁ Hana BŘEZINOVÁ Eva REPÍKOVÁ M. JANDUŠÍKOVÁ S. ZBOŘIL V. KASARDA R.

Year of publication 2022
Type Article in Periodical
Magazine / Source Referátový výběr z dermatovenerologie
MU Faculty or unit

Faculty of Medicine

Citation
Web http://referatovyvyber.cz/dermatovenerologie/images/flippingbook/RVD-4-2022/rvd-4-2022.pdf
Keywords Pyoderma gangraenosum; neutrophil dysfunction; treatment
Description Pyoderma gangraenosum is a re_latively rare disease of unknown etiology, first described more than 100 years ago. It is necessary to think about it in sudden, painful and non-healing ulcers, most often on legs. A lot of patients have systemic di_seases (Crohn's disease, ulcerative colitis, arthritis, malignancies). The treatment is empirical. Treatment can be divided into four categories: topical treatment, systemic non-immunosuppressive therapy, syste_mic immunosuppressive therapy and biological therapy. Ulcers heal with cribriform scars. The course is difficult to predict, often recurrent, depending on the type and severity of comorbidities.

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