Publication details

Global impact of the COVID-19 pandemic on subarachnoid haemorrhage hospitalisations, aneurysm treatment and in-hospital mortality: 1-year follow-up

Authors	MIKULÍK Robert QURESHI Muhammad M ŠEDOVÁ Petra KLEIN Piers ŠKORŇA Miroslav YAMAGAMI Hiroshi MIKULÍK Robert ETMINAN Nima ABDALKADER Mohamad MANSOUR Ossama Yassin CZLONKOWSKA Anna LO Hannah SATHYA Anvitha DEMEESTERE Jelle TSIVGOULIS Georgios SAKAI Nobuyuki ŠEDOVÁ Petra KRISTOFFERSEN Espen Saxhaug MOHAMMADEN Mahmoud VIRGINIA Pujol Lereis SERGIO Daniel Scollo MA Alice RAHMAN Aminur BONNET Thomas CORTIER Jeroen SYLVIE De Raedt LEMMENS Robin LIGOT Noemie HIDALGO Raquel C T LILIANA Mora Cuervo Daissy NEVES Luciana de Oliveira TULIO Salles Rezende Marco SANTIAGO Igor Bessa SIRAKOV Alexander SIRAKOV Stanimir CORA Elena Adela KELLY Michael E LAVOIE Pascale PEELING Lissa PIKULA Aleksandra RIVERA Rodrigo CHEN Hui-Sheng CHEN Yimin FANG Hongliang BEDEKOVIC Marina Roje BUDINCEVIC Hrvoje STROSSMAYER J J HRABANOVSKA Emanuela JURAK Lubomir CABAL Martin KADLCKOVA Jana KARPOWICZ Igor PALOUSKOVA Hana REISER Martin KLECKA Lukas KOVAR Martin NEUMANN Jiri REKOVA Petra SRAMEK Martin VITKOVA Eva ŠKORŇA Miroslav ZAKOVA Lenka SOBH Khalid ALPAY Kemal RAUTIO Riitta STRBIAN Daniel GENTRIC Jean-Christophe MAGRO Elsa NAGGARA Olivier REINER Peggy ABDULAZIM Amr BOHMANN Ferdinand O BOSKAMP Stefan GERBER Johannes C KAISER Daniel P O KESTNER Roxane-Isabelle MBROH Joshua NEYAZI Milad ROSENKRANZ Michael SANI Achmad Firdaus POLI Sven THOMALLA Gotz KARAPANAYIOTIDES Theodoros KARGIOTIS Odysseas KOUTROULOU Ioanna PALAIODIMOU Lina DOMINGO Barrientos Guerra Jose HUDED Vikram NAGENDRA Shashank PRAJAPATI Chintan KRISHNA Angga GHOREISHI Abdoreza ILKHCHI Reza Bahrami JALILI Javad SABETAY Sergiu Ionut TARIQ Abu Raya ACAMPA Maurizio LONGONI Marco BIGLIANI Claudia Rolla CASTELLAN Lucio ORNELLO Raffaele RENIERI Leonardo ROMOLI Michele SACCO Simona SANGALLI Davide VIGANO Martina ZINI Andrea TOKIMURA Hiroshi SONODA Kazutaka TODO Kenichi FUKUDA Hiroki FUJITA Kyohei SAKAGUCHI Manabu UNO Masaaki KAN Issei KOSUKE Miyake KONO Ryuhei KIMURA Naoto YAMAMOTO Nobuaki YAMAMOTO Ryoo DOIJIRI Ryosuke SHINDO Seigo OHARA Nobuyuki IMAMURA Hirotoshi OGAWA Takehiro UWATOKO Takeshi KANAMARU Takuya FUJINAKA Toshiyuki TAKENOBU Yohei TOYODA Kazunori MATSUMARU Yuji YAZAWA Yukako SUGIURA Yuri BAEK Jang-Hyun SUNMONU Taofiki Ajao KWON Young Sub LEE Yun Ho SEO Kwon-Duk SOHN Sung-Il CHAN Yong Chieh ZAIDI Wan Asyraf Wan BARRIENTOS-PRIETO Javier GONGORA-RIVERA Fernando MARTINEZ-MARINO Manuel CALDERON-VALLEJO Alejandra GROPPA Stanislav PAVEL Leahu COUTINHO Jonathan M DIPPEL Diederik RINKEL Leon VAN DAM-NOLEN Dianne H K NWAZOR Ernest Okwundu AL HASHIMI Amal M AHMAD Saima RASHID Umair RODRIGUEZ-KADOTA Liliana MIGUEL Angel Vences PATRICK Matic Yalung STEWART Hao Dy Jon BROLA Waldemar DOROBEK Malgorzata KARLINSKI Michal Adam LABUZ-ROSZAK Beata M LASEK-BAL Anetta SIENKIEWICZ-JAROSZ Halina STASZEWSKI Jacek SOBOLEWSKI Piotr ZIELINSKA-TUREK Justyna ARAUJO Andre Pinho FONSECA Luisa DEBIEC Aleksander SILVA M Luis CASTRO Pedro ROCHA Mariana FALUP-PECURARIU Romania Cristian VENKETASUBRAMANIAN Narayanaswamy MAKO Georgi Krastev Miroslav AYO-MARTIN Oscar WIACEK Marcin BLASCO Jordi CRUZ-CULEBRAS Antonio HERNANDEZ-FERNANDEZ Francisco CLAUDIO Rodriguez Fernandez JORGE Escartin Lopez RODRIGUEZ Alejandro BOLOGNESE Manuel KARWACKI Grzegorz Marek KELLER Emanuela MACHI Paolo BERNAVA Gianmarco BOONYAKARNKUL Surawan CHUROJANA Anchalee HAMMAMI Nadia BAJRAMI Arsida SENADIM Songul HUSSAIN Syed I JOHN Seby DOW Graham KRISHNAN Kailash LENTHALL Robert WONG Ken ZHANG Liqun ALTSCHUL Dorothea ASIF Kaiz S AZIZ-SULTAN Mohammad A BACH Ivo BELOW Kristine BILLER Jose CERVANTES-ARSLANIAN Anna M CHAUDHRY Saqib A CHEBL Alex CHEN Michael COLASURDO Marco CZAP Alexandra DASENBROCK Hormuzdiyar BAHIRU Zeelalem DE HAVENON Adam H DHARMADHIKARI Sushrut DMYTRIW Adam A ESKEY Clifford J ETHERTON Mark EZEPUE Chizoba FINK Lauren GASIMOVA Ulviyya GOYAL Nitin GRIMMETT Kasey B HAKEMI Maryam HESTER Taryn INOA Violiza KAN Peter T KASPER Ekkehard M KHANDELWAL Priyank KHATRI Rakesh KHOURY Naim N KIM Benny S KOLIKONDA Murali KUHN Anna Luisa LINARES Guillermo LINFANTE Italo LOOCHTAN Aaron I LUKOVITS Timothy G MALE Shailesh S KHAWAJA Ayaz M MAALI Laith GALECIO-CASTILLO Elsi Milagros MIN Jiangyong MOHAMED Ghada A NALLEBALLE Krishna ORTEGA-GUTIERREZ Santiago RADAIDEH Yazan RAMAKRISHNAN Pankajavalli MASOUD Hesham E REDDY Aravind B RULAND Sean OMRAN Setareh Salehi SHETH Sunil A PURI Ajit S RAHANGDALE Rahul H SIEGLER James E STAROSCIAK Amy K TARLOV Nicholas E TAYLOR Robert A TSAI Jenny WANG Michael J WONG Ka-Ho ZAIDAT Osama O LE Huynh Vu PHAN Hoang Thi TON Mai Duy TRAN Anh Duc SIRAKOVA Kristina PHAM Thong Nhu MOHLENBRUCH Markus A NAGEL Simon RAYMOND Jean NOGUEIRA Raul G
Year of publication	2022
Type	Article in Periodical
Magazine / Source	Journal of Neurology, Neurosurgery, and Psychiatry
MU Faculty or unit	Faculty of Medicine
Citation
Web	https://jnnp.bmj.com/content/93/10/1028
Doi	http://dx.doi.org/10.1136/jnnp-2022-329200
Keywords	COVID-19; subarachnoid haemorrhage hospitalisations; aneurysm treatment; in-hospital mortality:
Description	Background Prior studies indicated a decrease in the incidences of aneurysmal subarachnoid haemorrhage (aSAH) during the early stages of the COVID-19 pandemic. We evaluated differences in the incidence, severity of aSAH presentation, and ruptured aneurysm treatment modality during the first year of the COVID-19 pandemic compared with the preceding year. Methods We conducted a cross-sectional study including 49 countries and 187 centres. We recorded volumes for COVID-19 hospitalisations, aSAH hospitalisations, Hunt-Hess grade, coiling, clipping and aSAH in-hospital mortality. Diagnoses were identified by International Classification of Diseases, 10th Revision, codes or stroke databases from January 2019 to May 2021. Results Over the study period, there were 16 247 aSAH admissions, 344 491 COVID-19 admissions, 8300 ruptured aneurysm coiling and 4240 ruptured aneurysm clipping procedures. Declines were observed in aSAH admissions (-6.4% (95% CI -7.0% to -5.8%), p=0.0001) during the first year of the pandemic compared with the prior year, most pronounced in high-volume SAH and high-volume COVID-19 hospitals. There was a trend towards a decline in mild and moderate presentations of subarachnoid haemorrhage (SAH) (mild: - 5% (95% CI -5.9% to -4.3%), p=0.06; moderate: - 8.3% (95% CI -10.2% to -6.7%), p=0.06) but no difference in higher SAH severity. The ruptured aneurysm clipping rate remained unchanged (30.7% vs 31.2%, p=0.58), whereas ruptured aneurysm coiling increased (53.97% vs 56.5%, p=0.009). There was no difference in aSAH in-hospital mortality rate (19.1% vs 20.1%, p=0.12). Conclusion During the first year of the pandemic, there was a decrease in aSAH admissions volume, driven by a decrease in mild to moderate presentation of aSAH. There was an increase in the ruptured aneurysm coiling rate but neither change in the ruptured aneurysm clipping rate nor change in aSAH in-hospital mortality.