Publication details
Langerhansova histiocytóza v dětském věku
| Title in English | Langerhans histiocytosis in children |
|---|---|
| Authors | |
| Year of publication | 2021 |
| Type | Article in Periodical |
| Magazine / Source | Česko-slovenská pediatrie |
| MU Faculty or unit | |
| Citation | |
| Web | https://www.prolekare.cz/casopisy/cesko-slovenska-pediatrie/2021-8-2/langerhansova-histiocytoza-v-detskem-veku-130477 |
| Keywords | Langerhans histiocytosis; myeloid neoplasm; BRAFV600E mutation; LCH-associated neurodegeneration of brain |
| Description | Langerhans cell histiocytosis (LCH) is the most common of the histiocytic disorders and occurs when the body accumulates too many immature Langerhans cells, a subset of the larger family of cells known as histiocytes. Scientific discussions on the definition of LCH used to be debated in terms of its classification as either an immune dysfunction or a rare cancer (neoplastic and malignant or not malignant). According to most experts, Langerhans cell histiocytosis (LCH) is currently classified as a myeloid neoplasm. |