Publication details

RBP-Tar – a searchable database for experimental RBP binding sites

Authors

GREŠOVÁ Katarína RAČEK Tomáš MARTINEK Vlastimil ČECHÁK David SVOBODOVÁ Radka ALEXIOU Panagiotis

Year of publication 2024
Type Article in Periodical
Magazine / Source F1000Research
MU Faculty or unit

Central European Institute of Technology

Citation
Web https://f1000research.com/articles/12-755/v2
Doi http://dx.doi.org/10.12688/f1000research.131014.2
Keywords RNA Binding Proteins; CLIP; RBP; Web-server
Description RNA-binding proteins (RBPs) play a critical role in regulating gene expression by binding to specific sites on RNA molecules. Identifying these binding sites is crucial for understanding the many functions of RBPs in cellular function, development and disease. Current experimental methods for identifying RBP binding sites, such as ultra-violet (UV) crosslinking and immunoprecipitation (CLIP), and especially the enhanced CLIP (eCLIP) protocol, were developed to identify authentic RBP binding sites experimentally.
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