Topography of genetic loci in tissue samples: towards new diagnostic tool using interphase FISH and high-resolution image analysis techniques

• Authors: KOUTNÁ Irena; KOZUBEK Stanislav; ŽALOUDÍK Jan; KOZUBEK Michal; LUKÁŠOVÁ Emilie; MATULA Pavel; BÁRTOVÁ Eva; SKALNÍKOVÁ Magdalena; CAFOURKOVÁ Alena; JIRSOVÁ Pavla
• Year of publication: 2000
• Type: Article in Periodical
• Magazine / Source: Analytical Cellular Pathology
• MU Faculty or unit: Faculty of Informatics
• Web: abstract
• Field: Genetics and molecular biology
• Keywords: FISH; high-resolution image analysis
• Description: Using single and dual colour fluorescence in situ hybridisation (FISH) combined with image analysis techniques the topographic characteristics of genes and centromeres in nuclei of human colon tissue cells were investigated.

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