Publication details

Odlišné účinky virové a buněčné formy proteinu Jun na monoblasty transformované onkogenem v-myb

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Title in English Differential effects of the viral and cellular forms of the Jun protein on monoblasts transformed by the v-myb oncogene
Authors

ŠEVČÍKOVÁ Sabina SOUČEK Karel ŠMARDA Jan

Year of publication 2001
Type Article in Proceedings
Conference V. pracovní setkání biochemiků a molekulárních biologů
MU Faculty or unit

Faculty of Science

Citation
Field Genetics and molecular biology
Description v-myb oncogene of avian myeloblastosis virus causes acute monoblastic leukemia in chicken and transforms myelomonocytic cells in vitro. In order to study the effects of Jun protein on v-myb-transformed cells we induced v-jun and c-jun expression in BM2 cell line. We found that both forms of the Jun protein affect growth and morphological properties of these cells.
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