Publication details
Metabolism of iodine in rat tissues is markedly influenced by excessive bromide intake
| Authors | |
|---|---|
| Year of publication | 2000 |
| Type | Article in Proceedings |
| Conference | Mengen- und Spurenelemente 2000 (Anke M. et al., eds.) [IF=n.a.] |
| MU Faculty or unit | |
| Citation | |
| Field | Endocrinology, diabetology, metabolism, nutrition |
| Keywords | iodine; bromide; metabolism; rat |
| Description | In experiments on rats, a significant influence of an extraordinarily high bromide intake on the metabolism of iodine was established. Very high bromide intake (i) increased the relative weight of the thyroid, notably in animals fed the low-iodine diet, (ii) strikingly decreased the amount of radioiodide accumulated in the thyroid of all animals, (iii) significantly shortened the biological half-life of iodine in the thyroid, etc. These changes were caused, with high probability, by an increase of iodine elimination by kidney due to an excess of bromide. |
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