Publication details

Cytoskeleton in some pathogenic fungi

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Authors

KOPECKÁ Marie GABRIEL Miroslav SVOBODA Augustin TAKEO Kanji YAMAGUCHI Masashi OHKUSU Misako HATA Kunihiko YOSHIDA Soichi

Year of publication 2000
Type Article in Proceedings
Conference VIII. Cytoskeletální klub Čs. Biol. Spol. Vranovská Ves 15.-17.3.2000
MU Faculty or unit

Faculty of Medicine

Citation
Field Microbiology, virology
Keywords cytoskeleton; human pathogenic fungi
Description Cytoskeleton was studied in two human fungal pathogens Cryptococcus neoformans and Aureobasidium pullulans in comparison with ascomycetous budding and fission yeasts.The results showed:1)topology of actin patches and cables in C.neoformans resembled budding yeast, while microtubules were similar to fission yeast;2) in A. pullulans actin was deficient, while microtubules were abundant and similar to fission yeast. Cell reproduction in C. neoformans is based on well developed cytoskeleton, while deficient cytoskeleton in A. pullulans may result in fungal polymorphism and resistence to fungicides.
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