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Publication details
Cytochemická detekce zdrojů peroxidu vodíku v kultivačním systému v průběhu fertilizace in vitro u člověka
Title in English | Cytochemical detection of the hydrogen peroxide sources in culture system during human in vitro fertilisation |
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Authors | |
Year of publication | 2001 |
Type | Article in Periodical |
Magazine / Source | Scripta Medica |
MU Faculty or unit | |
Citation | |
Field | Gynaecology and obstetrics |
Keywords | cytochemistry; hydrogen peroxide; in vitro fertilisation |
Description | Cellular sources of hydrogen peroxide were detected cytochemically in culture system during IVF. The spermatozoa (especially frozen-thawed), damaged cumulus cells as well as fragmented oocytes and developmentally arrested embryos have been identified as hydrogen peroxide generators. Production of this metabolite is associated with cell damage and/or degeneration signalling the poor quality of gametes and accompanying somatic cells. |
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