Publication details
Acute and chronic methamphetamine effects on agonistic behaviour in mice
| Title in English | Acute and chronic methamphetamine effects on agonistic behaviour in mi |
|---|---|
| Authors | |
| Year of publication | 2002 |
| Type | Article in Proceedings |
| Conference | PROGRAMME AND ABSTRACTS of EuroConference MODELING ADDICTION: How closely do genetic, neurochemical, electrophysiological and behavioral experimental models predict human patterns of abuse and dependence |
| MU Faculty or unit | |
| Citation | |
| Field | Pharmacology and pharmaceutical chemistry |
| Keywords | methamphetamine; agonistic behaviour; mice |
| Description | There is evidence that methamphetamine (MET) increases spontaneous locomotor activity in both, humans and animals. The presnt study investigated MET effects on the full repertoire of agonistic behavioural acts including sociable, defensive-escape, aggressive, and locomotor activities in singly-housed male mice in paired interactions with non-aggressive group-housed partners. MET in our experiments elicited significant inhibition of aggressivity and stimulatory influence on locomotor behaviour, results resembling those of some earlier studies. |
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