Publication details

Induction of type II iodothyronine 5'-deiodinase and mitochondrial uncoupling protein in brown adipocytes differentiated in cell culture

Authors

HOUŠTĚK Josef PAVELKA Stanislav BAUDYŠOVÁ Marie KOPECKÝ Jan

Year of publication 1990
Type Article in Periodical
Magazine / Source FEBS Letters [IF=3.420 (1989); SCI #cit.<8>]
MU Faculty or unit

Faculty of Science

Citation
Field Genetics and molecular biology
Keywords Brown adipose tissue; catecholamine; cell culture; iodothyronine 5'-deiodinase; uncoupling protein
Description Brown adipocytes differentiated in primary cell culture were found to contain a type II iodothyronine 5'-deiodinase (5'D). Incubation of confluent cells with norepinephrine or dibutyryl-cAMP caused up to 17-fold increase in 5'D activity with a maximum after 8 h.

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