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Publication details
Induction of type II iodothyronine 5'-deiodinase and mitochondrial uncoupling protein in brown adipocytes differentiated in cell culture
Authors | |
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Year of publication | 1990 |
Type | Article in Periodical |
Magazine / Source | FEBS Letters [IF=3.420 (1989); SCI #cit.<8>] |
MU Faculty or unit | |
Citation | |
Field | Genetics and molecular biology |
Keywords | Brown adipose tissue; catecholamine; cell culture; iodothyronine 5'-deiodinase; uncoupling protein |
Description | Brown adipocytes differentiated in primary cell culture were found to contain a type II iodothyronine 5'-deiodinase (5'D). Incubation of confluent cells with norepinephrine or dibutyryl-cAMP caused up to 17-fold increase in 5'D activity with a maximum after 8 h. |